Recipient age and pulsatility index affect uterine receptivity in oocyte donation programmes

Uterine artery doppler pulsatility index at 11-14 weeks in ART pregnancies with egg-donation

Objective Uterine artery Doppler studies with measurement of pulsatility index (UtPI) represent recognized predictors of placental insufficiency and preeclampsia. Mode of conception (MC) has not been shown to modify the PI of uterine arteries; however we are not aware of studies investigating egg donations (ED). We hypothesize that perfusion of uterine arteries evaluated with Doppler studies ma...

Endometrial markers of uterine receptivity utilizing the donor oocyte model.

BACKGROUND Ethical constraints limit the ability to study peri-implantation phase human endometrium. In this study, the donor oocyte model was used to study candidate endometrial markers of uterine receptivity. METHODS Archived, paraffin-embedded tissue obtained by endometrial biopsy during cycle days 21-23 of patients undergoing 'mock' hormonal treatment cycles were evaluated by standard his...

Donor age is a major determinant of success of oocyte donation/recipient programme.

BACKGROUND In recent years, particularly in developed countries, women have tended to delay childbirth until over 40 years of age. Our study aims to identify whether the donor's age or recipient's age influences the pregnancy and live birth rate following oocyte recipient cycles. METHODS A population study included 3889 fresh oocyte recipient cycles. Pregnancy and live delivery rates were com...

I-28: Uterine Receptivity

Endometrial receptivity after oocyte donation in recipients with a history of chemotherapy and/or radiotherapy.

INTRODUCTION Information is scarce regarding the outcome of oocyte donation (OD) in patients with a history of cancer treatment. Therefore, we conducted a matched controlled analysis on the outcome of OD in these recipients. METHODS Between January 2000 and November 2005, 33 patients with a history of chemotherapy and/or radiotherapy had an OD cycle. Matching was performed to the chronologica...